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Cheesy Pepperoni Quick Bread
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4.50 from 2 votes

Pepperoni Bread

All I can say is make this recipe for Pepperoni Bread whether as a loaf or as drop biscuits, it may just become a new favorite recipe!
Prep Time10 mins
Cook Time55 mins
Course: Bread
Cuisine: American
Keyword: Cheesy Pepperoni Bread, Pepperoni Quick Bread
Servings: 9 servings
Calories: 423kcal


  • 1 whole egg, plus 1 egg yolk
  • 1 ½ cups whole milk
  • 3 TBS sugar
  • 3 TBS vegetable oil
  • 3 cups all-purpose flour
  • ¾ teaspoon salt
  • black pepper
  • 1 TBS plus 1 teaspoon baking powder
  • 6 ounces chopped pepperoni I like the thin slices for this typically found in a 6 oz package
  • 2 cups shredded cheese (I use 50% Mozzarella and 50% Provolone) You can use Cheddar, a cheddar blend all mozzarella Pepper Jack or whatever you enjoy.
  • 1 teaspoon oregano or Italian seasoning
  • 2 TBS butter optional
  • 1 teaspoon garlic paste or ¼ teaspoon garlic powder optional


  • Preheat oven to 350 degrees.
  • Line a loaf pan with parchment paper (it can hang over the sides.
  • In a mixing bowl, combine the eggs, milk, sugar and oil and whisk until combined.
  • Add the flour, salt, pepper, spice and baking powder (all at once) and mix with a spatula until just incorporated.
  • Add in the pepperoni and cheese and mix with a spatula until just incorporated.
  • Scrape batter into the lined loaf pan and bake on the middle rack for 55-60 minutes or until a toothpick inserted comes out dry.
  • Optional - I like to melt butter and mix it with garlic paste (or garlic powder) and pull the biscuits or loaf from the oven and quickly brush them with the mixture a few minutes before done cooking. A delicious flavor boost!
  • Allow the loaf to cool in the pan 5-10 minutes and then lift the loaf out, slice and enjoy If making as biscuits, bake for 10-15 minutes (depending on how large you make them). I typically use an ice cream scoop and place the batter on a parchment-lined baking pan.


We enjoy this both as a quick bread and as biscuits. Feel free to cut the sugar down, this is just how my family enjoys it.


Serving: 9servings | Calories: 423kcal | Carbohydrates: 38g | Protein: 15g | Fat: 23g | Saturated Fat: 12g | Cholesterol: 51mg | Sodium: 724mg | Potassium: 170mg | Fiber: 1g | Sugar: 6g | Vitamin A: 313IU | Vitamin C: 1mg | Calcium: 182mg | Iron: 2mg